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TAS4464 hydrochloride 是高效的、选择性的 NEDD8 活化酶 (NAE)抑制剂,其 IC50=0.955 nM。
TAS4464 hydrochloride 是高效的、选择性的 NEDD8 活化酶 (NAE)抑制剂,其 IC50=0.955 nM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 593 | 现货 | |
5 mg | ¥ 1,490 | 现货 | |
10 mg | ¥ 2,380 | 现货 | |
25 mg | ¥ 4,790 | 现货 | |
50 mg | ¥ 6,680 | 现货 | |
100 mg | ¥ 8,830 | 现货 | |
200 mg | ¥ 11,900 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 1,780 | 现货 |
产品描述 | TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM). |
靶点活性 | NAE:0.955 nM |
分子量 | 542.97 |
分子式 | C21H24ClFN6O6S |
CAS No. | 1848959-11-4 |
Smiles | Cl.CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
溶解度信息 | H2O: 4 mg/mL (7.37 mM), Sonication and heating to 60℃ are recommended. DMSO: 80 mg/mL (147.34 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||||||||||||
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